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10.28.2026

Sleuth Hound: The Case of the Real Sherlock Holmes by Lindsey Fitzharris

Throughout nineteenth-century Edinburgh, the surgeon Joseph Bell was known for his extraordinary talent for detection and diagnosis. To the amazement of onlookers at the Royal Infirmary, he could read a patient’s ailments, occupation, and personal habits from a single glance. Though such deductive powers were all quite “elementary” to Bell, they had a profound influence on the medical student and budding writer Arthur Conan Doyle. Soon enough, Bell’s methods helped spark the creation of fiction’s most iconic detective. Since Sherlock Holmes first appeared in 1887, he has become a global phenomenon. Yet the man Conan Doyle credited as Sherlock’s prototype has slipped into the shadows. In Sleuth-Hound, the New York Times bestselling author Lindsey Fitzharris brings Bell center stage, recounting how his work took him from ward to witness box as a medical detective probing murder and misdeeds. He worked closely and covertly with the police surgeon Henry Duncan Littlejohn and a pioneering ballistics expert named Dr. Watson, and even collaborated with Conan Doyle to overturn a homicide conviction. Bell’s forensic investigations took him from gaslit alleyways to Gilded Age drawing rooms, put him on the trail of poisoners and child killers, and even drew him into the hunt for Jack the Ripper. By scrutinizing a scratch on a desk, a trace of cigar ash, or the slightest peculiarity of a man’s gait, Bell could turn the smallest clues into revelations. His sharp mind forever changed the way we read bodies, detect crimes, and serve justice.

About the Speakers

Lindsey Fitzharris is the bestselling author of The Butchering Art and The Facemaker. Dr. Fitzharris, who holds a Ph.D. in the History of Science and Medicine from Oxford University, regularly writes for the Wall Street Journal, Scientific American, the Guardian, the Lancet, and other major publications. She is also the writer and host of the Smithsonian Channel TV series The Curious Life and Death of….

Catherine Prendergast is a Guggenheim Fellow, a Fulbright Scholar, and Professor Emerita at the University of Illinois at Champaign-Urbana. She is author most recently of The Gilded Edge: Two Audacious Women and the Cyanide Love Triangle that Shook America. Praised in the Wall Street Journal and The Los Angeles Times, its most sterling review certainly came from Lindsey Fitzharris who called it “Narrative nonfiction at its best.” Prendergast currently lives on Cape Cod year round.

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